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How do I know if my PrEP is working?

Signs Your Colon is Clear The morning of your exam if you are still passing brown liquid with solid material mixed in, your colon may not be ready and you should contact your doctor's office. Passing mostly clear or only a light color, including yellow, is a sign your colon is clean enough for an accurate examination.

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One of the most common questions we get at CRS is “how do I know if my bowel prep is working?

When prepping for a colonoscopy your doctor has probably talked to you about how important the bowel prep process is for accurate results. Residue left behind can make it harder for the doctor to view your colon during the exam – meaning a polyp or other issue might not be seen as clearly or even missed. And no one wants to get to a colonoscopy appointment and be told their prep didn’t fully empty the colon and they’ll have to do it again.

So how do you know if your bowel prep isn’t working?

Everyone Colon Is Different

When To Call Our Office

If it has been more than 4 hours since you started bowel prep and you aren’t feeling the effects

If you experience persistent nausea or vomiting during preparation

Many people start their prep and expect something to happen within minutes– but everyone is different and for some people, prep just takes longer to begin and complete. For the average patient prep takes about 6-8 hours to complete, and often women can take longer than men. Women often have longer colons due to childbirth or hysterectomies, so it can take more time for material to travel through the colon. Generally, if you’ve started prep but haven’t felt the urge to go to the bathroom after an hour, there is no cause for concern or a call to the doctor’s office. However, if it has been more than 4 hours since you started the bowel prep process and you aren’t feeling the effects please contact our office for instructions. Or if you experience persistent nausea or vomiting during preparation you should call and let us know.

Health Issues or Medications May Also Impact Prep

Not following the instructions, or drinking clear liquids as prescribed can slow or negatively impact bowel prep. And patients with diabetes, neurologic conditions or those who take certain medications or suffer from chronic constipation may take up to twice as long to complete the process. This is just one of the many reasons the physicians at CRS may meet with patients beforehand to review your health history and identify and factors that might impact the type of prep given. It is important to bring a list of every medication you are taking, as there are several different colon preparations and your CRS doctor will determine the best prep based on your specific situation. If necessary your CRS doctor may consult with your primary care, or GI doctor, to discuss stopping or altering dosage, or certain medications prior to your exam.

Signs Your Colon is Clear

The morning of your exam if you are still passing brown liquid with solid material mixed in, your colon may not be ready and you should contact your doctor’s office. Passing mostly clear or only a light color, including yellow, is a sign your colon is clean enough for an accurate examination.

Talk to a Colon Doctor in Richmond, VA

Established in 1913, CRS is one of the oldest continually operating groups of colon and rectal surgeons in the country and the largest state-of-the-art practice on the East Coast with three locations around Richmond, VA. The physicians and staff of Colon & Rectal Specialists are committed to providing all our patients with the special care and education needed for the treatment of colon and rectal problems. Contact us for more information or an appointment at one of our three Richmond area locations.

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Can I take PrEP 2 hours late?

The easy answer is that you will probably be fine. Both the drugs in PrEP stay in your body to allow for a few hours being late with dosing. It is better to try to take them at the right time. The after sex doses with on demand dosing only need to be taken 24 hours and 48 hours after the first double dose.

Q and A

Question

Will taking PrEP late work with on demand dosing?

Hi, I take PrEP with on demand dosing and after having sex after my first double dose i remembered my first dose post sex on time. However, my second dose was 5h late and 3rd dose was 5h late too. Will this affect my level of protection and should i continue taking it 5h late every day?

Answer

Hi

Thanks for your question. The easy answer is that you will probably be fine. Both the drugs in PrEP stay in your body to allow for a few hours being late with dosing.

It is better to try to take them at the right time.

The after sex doses with on demand dosing only need to be taken 24 hours and 48 hours after the first double dose. Taking an extra dose for a third day will not do any harm though. If you are still having sex every day though, then continue taking PrEP until 24 and 48 hours after the last time you had sex.

More information on real life examples for on demand dosing.

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