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Hearts can be kept alive for 24 hours after death, scientists have shown in a breakthrough which could help solve the organ donation crisis. Currently, hearts must be transplanted within a critical four-hour window, after which too much damage has occurred for the organ to be useful.
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Read More »So far the team has shown it works on pig hearts, which are very similar to human hearts, and researchers are now seeking permission from regulators to begin clinical trials. It would mean that hearts from all over the world could be shipped to those in need. Dr Rafael Veraza, from the University of Texas, said: “The machine is a game-changer and has the potential to save thousands of lives. “Time is currently a major obstacle and limits where an organ can be used. “Keeping a heart alive for 24 hours would allow doctors to transport it almost anywhere in the world to whoever needs it.” There are around seven million people living with heart and circulatory diseases in the UK and 152,000 will die each year. For many a heart transplant is the only option but donors are limited. In the 2018/2019 there were just 178 heart transplants were performed in Britain but 286 were left on the waiting list, and around 20 patients die while waiting for a heart each year. There are currently 328 people on the heart transplant list and the average person waits almost three years - 1,085 days - for a heart. But around three in four donated hearts are never used because they cannot reach a patient in time. Researchers say the new technique gives more time to reach a patient as well as allowing for better matches to be made, rather than settling for the first organ that is available. Organs will also be in a better condition at transplant, giving a greater chance of success. The device, which is the size of small suitcase, and easily portable, is likely to cost around £100,000. The next stage is to transplant the hearts into pigs, and then move to human trials, possibly within the next 18 months. “The pig hearts in our trial appeared to remain viable 24 hours after they were harvested,” added Dr Veraza.
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