Is PrEP safe with Viagra?

Can I take PrEP with erectile dysfunction drugs like Viagra or Cialis? There are no known interactions between PrEP drugs and erectile dysfunction drugs such as sildenafil (Viagra) or tadalafil (Cialis).

sfaf.org - PrEP Facts: Introduction & FAQ - San Francisco AIDS Foundation

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Is PrEP safe to take if I have hepatitis?

Before starting or restarting PrEP, your healthcare provider will want to know if you have hepatitis A, B, or C. You can get vaccinated to prevent two of them (A & B), and you can be treated for two of them (B & C). Hepatitis B screening is included in PrEP care. It’s important to get screened for these depending on your likelihood of exposure. HEPATITIS A: This virus is usually transmitted by consuming food or water that’s contaminated with feces. Uncooked shellfish can also be the cause. Although it rarely causes liver failure, hepatitis A can cause severe disease. Consider getting the vaccine if you haven’t already had hepatitis A. HEPATITIS B: This virus is usually transmitted through sex or exposure to infected blood, such as sharing needles, unsterilized tattoo tools, or during childbirth. Most people clear the infection on their own but some have lifelong (chronic) disease. Consider getting the vaccine if you haven’t already had hepatitis B. If you have chronic hepatitis B, stopping PrEP medicines can impact it. That’s because PrEP drugs are also used to treat hepatitis B: If you stop PrEP, it can cause the virus to flare up in the liver. It is safe to take PrEP with chronic hepatitis B, but make sure your doctor monitors your health more closely if/when you decide to stop PrEP. People with chronic hepatitis B should only use daily PrEP, not 2-1-1. HEPATITIS C: This virus is spread by blood-to-blood contact, mostly through sharing needles, unsterilized medical or tattoo equipment, and needle stick accidents. Sexual transmissions have occurred among gay men, likely due to micro-tears during anal sex. Emerging data suggest that PrEP users may be at higher risk for contracting hepatitis C through sexual transmission. Hepatitis C testing is recommended when starting PrEP, and your provider may suggest regular testing. There is no vaccine for hepatitis C, but several different treatments can cure it. Some hepatitis C medicines may increase the blood level of tenofovir in PrEP, so be sure to discuss this with your provider if you are considering hepatitis C treatment. Lastly, be aware that you can get hepatitis C again after being treated for it.

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How many hours should PrEP be taken?

cdc.gov - On-Demand PrEP | PrEP | HIV Basics - CDC

Taking PrEP pills only when you are at risk for getting HIV is known as “on-demand” PrEP.

It is also known as “intermittent,” “non-daily,” “event-driven,” or “off-label” PrEP use.

The type of “on-demand” PrEP that has been studied is the “2-1-1” schedule. This means taking 2 pills 2-24 hours before sex, 1 pill 24 hours after the first dose, and 1 pill 24 hours after the second dose. There is scientific evidence that the “2-1-1” schedule provides effective protection for gay and bisexual men* when having anal sex without a condom. We don’t know how “on-demand” PrEP works for heterosexual men and women, people who inject drugs, and transgender persons. Some health departments in the United States and some health organizations in Europe and Canada are offering guidance for “on-demand” PrEP as an alternative to daily PrEP for gay and bisexual men at risk for HIV. Although the updated PrEP guideline provides information on how to correctly use the “2-1-1” schedule, this approach is not approved by the U.S. Food and Drug Administration (FDA) and is not recommended by CDC. Taking PrEP as prescribed is currently the only FDA-approved schedule for taking PrEP to prevent HIV. When taken as prescribed, PrEP is highly effective for preventing HIV.

Anyone considering PrEP should discuss the issue with their health care provider.

* The term “gay and bisexual men” is used to describe men who identify as gay or bisexual, as well as men who have sex with men who do not identify as gay or bisexual.

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